Protein levels from vials of whole blood are generally clinically determined using single-protein immunoassays. However, according to research by Geyer et al., a single drop of blood and a mass spectrometer may be all that’s needed to assess human health and disease.
Read my review on Geyer et al.’s paper over at Thermo Fisher Scientific’s Accelerating Science Blog.
Review of: Geyer, P.E., et al. (2016) “Plasma proteome profiling to assess human health and disease,” Cell Systems, 2(3) (pp.185–195). doi: http://dx.doi.org/10.1016/j.cels.2016.02.015.